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The heterogeneity of the 5q− chromosome marker in refractory anemia

Authors
Journal
Cancer Genetics and Cytogenetics
0165-4608
Publisher
Elsevier
Publication Date
Volume
9
Issue
2
Identifiers
DOI: 10.1016/0165-4608(83)90031-6
Disciplines
  • Medicine

Abstract

Abstract A patient presenting with an unusual case of refactory anemia is described in whom acquired markers originating from chromosomes No. 5 and 8 are identified by G- and sequential C-banding. Comparison with various published illustrations of chromosome No. 5 deletions in this general broad category of disease raises the possibility that karyotypic misclassification in cases of absent or substandard banding (typical of bone marrow) may help to explain the considerable variation in size and morphology of the 5q− marker.

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