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Preoperative therapy for rectal cancer: Short-course radiation vs. long-course chemoradiation

Authors
Journal
Seminars in Colon and Rectal Surgery
1043-1489
Publisher
Elsevier - WB Saunders
Volume
25
Issue
1
Identifiers
DOI: 10.1053/j.scrs.2013.09.004
Disciplines
  • Medicine

Abstract

Abstract Preoperative radiation therapy for rectal cancer is delivered by two techniques: short-course radiation and long-course chemoradiation. These two approaches cannot be directly compared since patients selected for treatment with short-course radiation commonly included those with cT1–3 disease, whereas chemoradiation is used for cT3 and/or N+ disease. Recent trials of short-course radiation have included patients with cT3 and/or N+ disease as well as delivered sequential or postoperative chemotherapy. This review will evaluate the results of the two preoperative approaches.

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