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Fertility preservation in ovarian cancer patients.

Authors
  • Santos, Maria Luís1
  • Pais, Ana Sofia1, 2
  • Almeida Santos, Teresa1, 2
  • 1 Faculty of Medicine, University of Coimbra, Coimbra, Portugal. , (Portugal)
  • 2 Reproductive Medicine Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. , (Portugal)
Type
Published Article
Journal
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Publication Date
Jun 01, 2021
Volume
37
Issue
6
Pages
483–489
Identifiers
DOI: 10.1080/09513590.2021.1872534
PMID: 33501866
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Ovarian cancer is more frequent in post-menopausal women, however it can also occur in young premenopausal women. After diagnosis and cancer staging, health care providers should address the possibility of infertility and might offer fertility preservation options. Chemotherapy, frequently used when treating ovarian cancer, has proven to cause extensive ovarian damage. Standard surgery may be aggressive and the recurrence risk may not be relevant enough to opt for these approaches. Fertility sparing surgery has been progressively accepted and many alternative surgical approaches have proven to be successful in both cancer treatment, fertility preservation and low recurrence rates. Though there are several techniques available for fertility preservation in cancer patients, when dealing with ovarian cancer patients, oocyte and embryo cryopreservation are the only suitable. Ovarian tissue cryopreservation has been largely studied, but no data on ovarian cancer patients exist, due to the risk of reimplanting cancer cells.

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