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Feasibility of using cryopreserved lymphoblastoid cells to diagnose some lysosomal storage diseases.

Authors
  • de Mello, A S1
  • Provin, F
  • Michelin-Tireli, K
  • Camelier, M V
  • Coelho, J C
  • 1 Post Graduate Program in Biological Sciences - Biochemistry, Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. , (Brazil)
Type
Published Article
Journal
Cell Proliferation
Publisher
Wiley (Blackwell Publishing)
Publication Date
Apr 01, 2010
Volume
43
Issue
2
Pages
164–169
Identifiers
DOI: 10.1111/j.1365-2184.2010.00660.x
PMID: 20447062
Source
Medline
License
Unknown

Abstract

However, these alterations did not invalidate use of the technology of transformation of lymphoblastoid cell lines with EBV, to diagnose the diseases mentioned above, in view of the fact that the cultured cells, before and after freezing, demonstrated similar enzymatic activities.

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