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Feasibility of limb salvage and survival in soft tissue sarcomas.

Authors
  • Karakousis, C P
  • Emrich, L J
  • Rao, U
  • Krishnamsetty, R M
Type
Published Article
Journal
Cancer
Publication Date
Feb 01, 1986
Volume
57
Issue
3
Pages
484–491
Identifiers
PMID: 3942981
Source
Medline
License
Unknown

Abstract

One hundred nine consecutive patients with soft tissue sarcomas were treated in the period 1977 through 1983. Of 85 patients with extremity sarcomas, only 3 patients (4%) were managed with amputation, whereas in the previous decade, 40% of such patients were treated with amputation in our institute. The current 5-year survival rate is 63%; in the previous decade it was 45%. In the current series, for extremity locations, patients with minimum surgical margins of 2 cm or greater and no further local therapy had a 5-year local recurrence rate of 17%, whereas those with minimum surgical margins of less than 2 cm and who were treated with adjuvant postoperative radiation had a local recurrence rate of 7%. In the previous period, the local recurrence rate was 30% after wide resection and 66.6% after local excision. With a combination of modalities, limb salvage can be practiced currently in the majority of patients with extremity soft tissue sarcomas without any adverse effect on recurrence rates and survival.

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