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Changes in blood catecholamines, insulin, corticosterone and glucose during the course of the Sephadex inflammation

Authors
Journal
Experimental Pathology
0232-1513
Publisher
Elsevier
Publication Date
Volume
21
Issue
4
Identifiers
DOI: 10.1016/s0232-1513(82)80036-4
Keywords
  • Inflammation
  • Sephadex
  • Adrenaline
  • Noradrenaline
  • Dopamine
  • Insulin
  • Corticosterone
  • Glucose
  • Catecholamines
  • Rat

Abstract

Summary During an acute inflammation, the blood levels of noradrenaline, dopamine and insulin increase uniformly until the fourth day, then reach a climax which for dopamine is above the norm, while the suppressed levels of noradrenaline and insulin approach the norm. All values decrease on the fifth day (end of the experiment). Glucose behaves inversely, showing a minimum on the fourth day. Corticosterone displays two peaks, on the first and fourth days. The adrenaline level differs distinctly from these patterns: it is elevated on the second, fourth and fifth days. By releasing each catecholamine independently, the organism can possibly influence the course of the inflammation.

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