Affordable Access

Human proto-oncogene c-mos maps to 8q11.

Authors
Publication Date
Source
PMC
Keywords
  • Research Article

Abstract

The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hydridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos has been found in acute leukaemia with the chromosomal translocation t(8;21)(q22;q22).

There are no comments yet on this publication. Be the first to share your thoughts.