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A simple and direct method for converting thioamides into thioesters

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
55
Issue
4
Identifiers
DOI: 10.1016/s0040-4020(98)01096-5
Keywords
  • Article

Abstract

Abstract Thioamides may be transformed into thioesters through the simple expedient of warming them in an aqueous THF solution containing an alkylating agent. Reactions proceed in high yield and are amenable to multi-gram scale.

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