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Mechanisms leading to toxin-induced impairment of renal function, with a focus on immunopathology

Authors
Journal
Toxicology Letters
0378-4274
Publisher
Elsevier
Publication Date
Volume
46
Identifiers
DOI: 10.1016/0378-4274(89)90129-x
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Environmental, occupational and therapeutic exposure to nephrotoxic compounds may cause different forms of renal disease and constitutes a major health problem. This paper discusses pathogenetic mechanisms leading to impairment of renal function and early detection of its symptoms, with special emphasis on immunopathology. Finally, it focuses on ways of identifying potentially nephrotoxic compounds.

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