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Favorable outcomes with tacrolimus in two patients with refractory interstitial lung disease associated with polymyositis/dermatomyositis.

Authors
  • Ochi, S
  • Nanki, T
  • Takada, K
  • Suzuki, F
  • Komano, Y
  • Kubota, T
  • Miyasaka, N
Type
Published Article
Journal
Clinical and experimental rheumatology
Publication Date
Jan 01, 2005
Volume
23
Issue
5
Pages
707–710
Identifiers
PMID: 16173253
Source
Medline
License
Unknown

Abstract

Two cases of progressive interstitial lung disease associated with polymyositis/dermatomyositis are presented. Both patients were refractory to conventional therapy with high-dose corticosteroids, cyclosporine, and intermittent pulse cyclophosphamide, and thus a therapeutic trial of tacrolimus was instituted. Tacrolimus was markedly effective in achieving subjective, laboratory and radiographic improvement in both patients.

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