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Fatal submassive necrosis of the liver associated with piroxicam.

Authors
Type
Published Article
Journal
The American journal of gastroenterology
Publication Date
Volume
85
Issue
4
Pages
468–470
Identifiers
PMID: 2327391
Source
Medline
License
Unknown

Abstract

A 64-yr-old woman developed acute hepatitis after 3 wk of treatment with 40 mg/day of piroxicam (Feldene). Jaundice was preceded by a skin rash associated with eosinophilia. Despite withdrawal of the drug, she developed severe hepatocellular failure and died 53 days after the onset. Hepatitis was attributed to piroxicam because of the absence of other etiological factors.

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