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Fatal nonmeningitic Listeria rhombencephalitis. Report of two cases.

Authors
  • Brun-Buisson, C J
  • de Gialluly, E
  • Gherardi, R
  • Otterbein, G
  • Gray, F
  • Rapin, M
Type
Published Article
Journal
Archives of Internal Medicine
Publisher
American Medical Association
Publication Date
Nov 01, 1985
Volume
145
Issue
11
Pages
1982–1985
Identifiers
PMID: 4062448
Source
Medline
License
Unknown

Abstract

Two cases of rapidly fatal Listeria rhombencephalitis with normal cerebrospinal fluid (CSF) findings occurred in previously healthy adults. The infection presented with nausea and headache followed by fever and signs of lower cranial nerve dysfunction, without associated meningismus, and progressed to death within four and six days of hospitalization. Because of normal CSF findings (including ventricular fluid in one patient) and negative culture results of both blood and CSF, the diagnosis was not suspected. Listeriosis should be considered early in any febrile patient presenting with signs of brain-stem dysfunction, even if CSF findings are normal.

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