We present our experience with fat injections in the treatment of two cases of facial lipodystrophies. The surgical technique as well as the followup of the two clinical cases are presented in order to evaluate the long post-operative results. Among the different techniques used by us for correcting the soft tissues of the facial contour, this has been by far the simplest and easiest. We need longer follow-ups and more clinical cases in order to point out some definite conclusions, however. Nevertheless, it is our impression in this preliminary report that this technique could have a place in the treatment of problems related to the soft tissues of the facial contour.