Affordable Access

Familial spastic paraplegia.

Authors
  • Phanthumchinda, K
  • Somrealvongkul, B
Type
Published Article
Journal
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Publication Date
Feb 01, 1989
Volume
72
Issue
2
Pages
62–66
Identifiers
PMID: 2738487
Source
Medline
License
Unknown

Abstract

Familial spastic paraplegia (FSP) was recorded in three families. The pattern of familial transmission and the onset in the second and third decade of life strongly suggested autosomal dominant inheritance. FSP in this series showed the consistent, classical, clinical features with some inconstant findings (nystagmus, dysarthria, posterior column involvement). Baclofen for the treatment of spasticity is beneficial in this condition and genetic counselling should be considered.

Report this publication

Statistics

Seen <100 times