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Familial Parkinson's disease: a clinical genetic analysis.

Authors
  • Bonifati, V
  • Fabrizio, E
  • Vanacore, N
  • De Mari, M
  • Meco, G
Type
Published Article
Journal
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Publication Date
Nov 01, 1995
Volume
22
Issue
4
Pages
272–279
Identifiers
PMID: 8599769
Source
Medline
License
Unknown

Abstract

The frequency of positive family history for PD and for PD and tremor is higher among PD cases than controls. Familial and sporadic PD only differ in onset age. The clinical genetic analyses support autosomal dominant inheritance with strongly age-related penetrance as most likely in familial PD.

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