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Is faecal alpha 1-antitrypsin excretion a reliable screening test for protein-losing enteropathy?

Authors
Type
Published Article
Journal
Lancet (London, England)
Publication Date
Volume
2
Issue
8153
Pages
1161–1162
Identifiers
PMID: 91891
Source
Medline
License
Unknown

Abstract

Estimation of alpha 1-antitrypsin in random faecal samples has been suggested as a reliable index of intestinal protein loss. There was a poor correlation between faecal alpha 1-antitrypsin concentrations and simultaneously measured faecal loss of 51Cr-albumin in twenty adults with suspected protein-losing enteropathy. This indicates that faecal alpha 1-antitrypsin estimation may not be a valid screening test for protein-losing enteropathy.

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