Affordable Access

Publisher Website

IL-10 control of dendritic cells in the skin

Authors
Journal
OncoImmunology
2162-4011
Publisher
Landes Bioscience
Publication Date
Volume
2
Issue
3
Identifiers
DOI: 10.4161/onci.23186
Keywords
  • Author'S View

Abstract

Interleukin-10 (IL-10) is a potent immunomodulatory cytokine, whose cellular targets have not yet been precisely identified. Dendritic cell (DC)-specific IL-10 receptor knockout mice exhibit exaggerated T-cell reactivation in the skin, highlighting a key role of DCs in the maintenance of local immune homeostasis, beyond their classical function as regulators of T-cell priming in lymph nodes.

There are no comments yet on this publication. Be the first to share your thoughts.