Wound infection is the most common postoperative complication after caesarean section (CS) in the cow. Generally a wound infection is believed to develop when the number of bacteria that enter the wound during the operation go beyond the local and systemic resistance of the host. The aim of this study was to look for variables that influence the rate of wound infection after CS in the cow. The postoperative outcome of 415 CS performed in practice was used for this study. The influence of 16 different variables was examined. A stepwise multiple logistic regression analysis revealed 4 variables that significantly influenced the wound infection rate. Two veterinarians had significantly more wound infections than their colleagues. One of these 2 was an experienced veterinarian the other had only limited experience. The results of the latter improved with the number of operations performed by him increased. Dairy cows, pregnant of a dairy bull, had more wound infections (38 %) than double-muscled cows (15 %) or dairy cows pregnant of a double-muscled bull (27 %). The indication for the CS also had a significant influence on the wound infection rate. When the operation was carried out because of an oversized calf, less wound infections occurred (Odds ratio: 0,2). When an unsuccessful attempt to extract the calf had taken place before the operation, wound infection was seen more frequently (Odds ratio: 3,6).