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Factors associated with hepatic fibrosis in patients with chronic hepatitis C: a retrospective study of a large cohort of U.S. patients.

Authors
  • Hu, Shirley X
  • Kyulo, Namgyal L
  • Xia, Victor W
  • Hillebrand, Donald J
  • Hu, Ke-Qin
Type
Published Article
Journal
Journal of Clinical Gastroenterology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Sep 01, 2009
Volume
43
Issue
8
Pages
758–764
Identifiers
DOI: 10.1097/MCG.0b013e31818be17c
PMID: 19238091
Source
Medline
License
Unknown

Abstract

The present study indicated that elderly, longer duration of HCV infection, obesity, and history of diabetes mellitus are independent clinical parameters associated with advanced fibrosis, whereas elevated AST, alpha fetoprotein, and presence of grade 2 and 3 steatosis are independent laboratorial parameters associated with stage 3 and 4 fibrosis in patients with CHC.

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