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Factor VIII and antibody levels in plasma fractions prepared by cryoprecipitation

Authors
  • Andrew Pollock
Publication Date
Sep 01, 1968
Source
PMC
Keywords
Disciplines
  • Medicine
License
Unknown

Abstract

Most of the antibody activity of plasma was found to remain in the supernatant fraction following the preparation of factor-VIII-rich cryoprecipitates. The low level of antibody remaining in these cryoprecipitates indicated that they could safely be used as a source of factor VIII for replacement therapy. Washing the cryoprecipitates farther reduced their antibody titres without materially affecting their factor VIII content.

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