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Facial port-wine stains - clinical stratification and risks of neuro-ocular involvement.

Authors
  • Ch'ng, Sydney
  • Tan, Swee T
Type
Published Article
Journal
Journal of Plastic Reconstructive & Aesthetic Surgery
Publisher
Elsevier
Publication Date
Aug 01, 2008
Volume
61
Issue
8
Pages
889–893
Identifiers
PMID: 17604243
Source
Medline
License
Unknown

Abstract

The clinical stratification of facial port-wine stains provides a guide to patient counselling and therapeutic interventions. Port-wine stains affecting the entire V1 distribution predict strongly for underlying neurological and/or ocular disorders that require on-going ophthalmological surveillance and/or neurological management. Although the classical Sturge-Weber syndrome encompasses a triad of clinical manifestations, incomplete forms are not uncommon. This neuro-oculo-cutaneous syndrome is believed to be a result of vascular malformations of associated structures derived from the neuroectoderm (facial skin, eye, and parieto-occipital region of the brain and leptomeninges) during the first trimester. However, the pathogenesis of port-wine stains and Sturge-Weber syndrome remains unclear.

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