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Epidemiological analysis of strains of methicillin-resistantStaphylococcus aureus(MRSA) infection in the nursery; prognosis of MRSA carrier infants

Authors
Journal
Journal of Hospital Infection
0195-6701
Publisher
Elsevier
Publication Date
Volume
31
Issue
2
Identifiers
DOI: 10.1016/0195-6701(95)90167-1
Keywords
  • Methicillin-Resistantstaphylococcus Aureus
  • Neonatal Infection
  • Pulsed-Field Gel Electrophoresis
Disciplines
  • Philosophy

Abstract

Abstract Forty-five neonates who carried methicillin-resistant Staphylococcus aureus (MRSA) were studied. Retrospective molecular analysis using pulsed-field gel electrophoresis showed three separate MRSA epidemics in the nursery. Strains of MRSA isolated from the neonates were also isolated from the hospital environment and health care providers. Clinical manifestations included skin pustules (eight patients), conjunctivitis (four patients), or other minor infections (two patients). No neonate developed systemic infection. The prevalence of MRSA decreased with age. At one year, three (14·3%) of 21 infants that had carried MRSA at six days remained carriers and only two (1·1%) of 180 infants in a control ‘ S. aurems-negative at six days’ group carried MRSA.

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