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RELATIONSHIP OF HUMAN ASCORBIC-ACID METABOLISM TO OVULATION

Authors
Journal
The Lancet
0140-6736
Publisher
Elsevier
Publication Date
Volume
297
Issue
7690
Identifiers
DOI: 10.1016/s0140-6736(71)90843-9

Abstract

Abstract Ascorbic-acid excretion has been Summary measured daily in the first morning specimen of urine in five ovulating and five non-ovulating females who were receiving 500 mg. ascorbic acid each morning at breakfast throughout the menstrual cycle. Basal body-temperatures were taken daily before the subjects got out of bed. The ascorbic-acid excretion reached a peak and then diminished three days before ovulation. It increased at the time of ovulation. Two smaller post-ovulatory peaks also occurred. Control subjects did not show comparable fluctuations in ascorbic-acid excretion. The pattern of ascorbic-acid excretion closely resembles the excretion of luteinising hormone at the time of human ovulation.

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