Affordable Access

Publisher Website

The importance of physicochemical swelling in cartilage illustrated with a model hydrogel system

Authors
Journal
Biomaterials
0142-9612
Publisher
Elsevier
Publication Date
Volume
19
Issue
13
Identifiers
DOI: 10.1016/s0142-9612(98)00017-9
Keywords
  • Physicochemical Modelling Of Cartilage Behaviour
  • Intrinsic Swelling Stress
  • One-Dimensional Consolidation
  • Hydrogel
Disciplines
  • Chemistry
  • Physics

Abstract

Abstract The physicochemically derived swelling stress in articular cartilage plays a crucial role in determining the pattern of stress sharing between the exudable fluid and the ‘solid’ components comprising its matrix. This pattern of stress sharing in turn influences the manner in which cartilage consolidates or deforms in compression via the outflow of fluid. Synthetic hydrogels exposed to a variety of cationic blocking solutions provide simplified model systems for exploring quantitatively the influence of the intrinsic swelling parameter on consolidation behaviour, thus yielding further insights into the fundamental parameters controlling the biomechanical properties of complex tissues such as articular cartilage.

There are no comments yet on this publication. Be the first to share your thoughts.