The purpose of this study is to analyze the Regional Economic Effects of the High-Tech Venture Business in Daedeok Valley and therby structural changes in the economy of Taejon City, using a Regional Input Output Analysis Method(RIOAM) and thereby to analyze structural changes in the economy of Taejon City. As a result, this study has found followings. First, in terms of linkage effects, the industries that have higher investment priorities are in the group of "intermediate-demand type" industries. For the year of 1995, the growing industries were basic metal, electricity and electric equipment, product of pulp and paper, which are mainly in the manufacturing sector. For the year of 2000. however, growing industries were primarily in the service sector such as electricity, gas and water, transport and storage, real estate, and business service. Especially, computer and business machine, electric instrument, media, audio, mobile equipment, and precusion tools of the high-tech ventre business in Daedeok Valley would desirable as strategic industries for the regional ecomony growth Taejon. Second, industries on Taejon could be grouped into "four sectors","depressed type" and "declining type", according to the multiplier effects are found to be basic metal, electric instrument, media, audio, mobile equipment, metal product, computer and office machinery products, and communications. In order to promote the economy of Taejon, it is recommanded that investment should be concentrated on the high-tech venture business industries in Daedeok Valley.