Affordable Access

Publisher Website

Screen-printed poly(3,4-ethylenedioxythiophene) (PEDOT): A new electrochemical mediator for acetylcholinesterase-based biosensors

Authors
Journal
Talanta
0039-9140
Publisher
Elsevier
Publication Date
Volume
82
Issue
3
Identifiers
DOI: 10.1016/j.talanta.2010.05.070
Keywords
  • Pedot:Pss
  • Acetycholinesterase
  • Mediator
  • Organophosphates
Disciplines
  • Design

Abstract

Abstract This work describes the use of a PEDOT:PSS-based conductive polymer for designing AChE-based biosensors. The transducers were obtained directly by screen-printing a PEDOT:PSS suspension on the surface of thick film carbon electrodes. The obtained working electrodes showed a high conductivity when compared with electrodes modified with conventional mediators like cobalt phthalocyanine or tetracyanoquinodimethane. The PEDOT:PSS polymer was shown to be suitable for thiocholine oxidation, allowing the measurement of AChE activity at 100 mV vs Ag/AgCl. The high conductivity of PEDOT:PSS allowed the accurate detection of the organophosphate insecticide chlorpyrifos-oxon at concentrations as low as 4 × 10 −9 M, corresponding to an inhibition ratio of 5%.

There are no comments yet on this publication. Be the first to share your thoughts.