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Small Silencing RNAs: Piecing Together a Viral Genome

Authors
Journal
Cell Host & Microbe
1931-3128
Publisher
Elsevier
Publication Date
Volume
7
Issue
2
Identifiers
DOI: 10.1016/j.chom.2010.02.001

Abstract

Virus-derived small interfering RNAs (siRNAs) are the hallmark of RNAi-based antiviral immunity. Wu and colleagues demonstrate how viral genomes can be assembled from these small RNA sequences. Their results provide an approach for virus discovery as well as important insights into how these siRNAs mediate antiviral defense.

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