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Cutaneous Manifestations of Internal Diseases

Authors
Journal
Veterinary Clinics of North America Small Animal Practice
0195-5616
Publisher
Elsevier
Volume
43
Issue
1
Identifiers
DOI: 10.1016/j.cvsm.2012.09.010
Keywords
  • Cutaneous Markers Of Internal Disease
  • Paraneoplastic Skin Disease
  • Metabolic Skin Disease
  • Endocrine Skin Disease
Disciplines
  • Medicine

Abstract

One of the best-recognized cutaneous manifestations of internal disease includes the skin changes seen in endocrine diseases. Cutaneous manifestations of internal disease can also be seen with certain neoplastic processes. Metabolic disturbances in zinc, lipid metabolism, or increased amino acid catabolism can result in zinc-responsive dermatosis, cutaneous xanthomas, and superficial necrolytic dermatitis, respectively. Certain infectious diseases can result in skin lesions that may provide visual clues but also critical diagnostic information if the skin is biopsied and cultured. Recognizing those skin changes that are clinical markers for internal disease can expedite the diagnosis and timely management of several systemic diseases.

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