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Ascaris suum:Location of phosphorylcholine in lung larvae

Authors
Journal
Experimental Parasitology
0014-4894
Publisher
Elsevier
Publication Date
Volume
43
Issue
1
Identifiers
DOI: 10.1016/0014-4894(77)90019-4
Keywords
  • Ascaris Suum
  • Parasitic Nematode
  • Phosphorylcholine
  • Lung Larvae
  • Mice
  • Myeloma Protein S107
Disciplines
  • Biology

Abstract

Abstract A fluoresceinated myeloma protein, S107, with reactivity to phosphorylcholine (PC), has been used to locate PC in Ascaris suum larvae in the lungs of mice. PC appears to be confined to internal membranous structures and the lining of the intestinal tract. The outside of the cuticle is negative for PC. Hence, access of PC and PC-containing parasite antigens to the host immune system may occur through intestinal excretions, damage to larvae, or, conceivably, at larval moulting stages.

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