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Mukoepidermoidni karcinom male ælijezde slinovnice

Authors
Publisher
School of Dental Medicine, University of Zagreb, Croatian Dental Society - Croatian Medical Association
Publication Date
Disciplines
  • Biology
  • Medicine

Abstract

The mucous membrane of the oral cavity, covered with multilayered squamous epithelium, is a source of benign and malignant lesions, from simple fibroma to carcinoma of the oral cavity. Because of accessibility of the pathological lesions dental practitioners can, by a routine clinical examination, with no additional diagnostic methods, diagnose and refer the patient to an oral or maxillofacial surgeon. For early detection and treatment of different formations it is most important for the patient to be referred promptly to the surgeon, so that minor surgical procedures can be performed, which can lead to cure. Pathological processes of deeper layers also manifest on the mucous membrane. Mucosal cysts, benign and malignant tumours can develop in the small salivary glands of all parts of the oral cavity. Tumours of the salivary glands comprise around 3% of the tumours in the body. In other words they are relatively rare. However, it is important to realise that 10 to 20% of all the above tumours occur in the small glands, most frequently on the palate. Equally important is the data that the relative incidence of malignant tumours increases, as the size of the glands in which they develop decrease. Case presentation A 21-year-old male patient was admitted for examination because of a painless formation on the hard palate, at the level of the molar, 2 cm in diameter, with wide base, exulcerous surface and thickened edges. From the case history it was learnt that he had not had subjective problems for around 2 years. Six weeks prior to admittance the growth/formation exulcerated and he felt fluid coming from it. A biopsy was performed which showed mucoepidermoid carcinoma, a malignant neoplasm of the small salivary glands that can occur at any age, although it is more frequent in children. The tumour was removed with an electro-scalpel, and the histopathological finding confirmed the diagnosis and revealed grade 1 malignancy (G-1). Such types of tumours rarely recur and metastasise, and according to data from the literature the degree of recovery within five years amounts to 90%. Malignomas of the small salivary glands are frequently difficult to clinically mutually differentiate, and they may resemble benign pleomorphic adenomas. Prompt examination and specialist treatment, followed by prompt biopsy and surgical procedure increases the chances of recovery.

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