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Extrameningeal solitary fibrous tumors—surgery alone or surgery plus perioperative radiotherapy: A retrospective study from the global solitary fibrous tumor initiative in collaboration with the Sarcoma Patients EuroNet

Authors
  • Haas, Rick L.1, 2
  • Walraven, Iris1
  • Lecointe‐Artzner, Estelle3
  • van Houdt, Winan J.1
  • Strauss, Dirk4
  • Schrage, Yvonne1, 4, 2
  • Hayes, Andrew J.4
  • Raut, Chandrajit P.5, 6, 7
  • Fairweather, Mark5, 6, 7
  • Baldini, Elizabeth H.6, 7, 5
  • Gronchi, Alessandro8
  • De Rosa, Laura8
  • Griffin, Anthony M.9
  • Ferguson, Peter C.9
  • Wunder, Jay9
  • van de Sande, Michiel A. J.2
  • Krol, Augustinus D. G.2
  • Skoczylas, Jacus10
  • Sangalli, Claudia8
  • Stacchiotti, Silvia8
  • 1 The Netherlands Cancer Institute, The Netherlands , (Netherlands)
  • 2 The Leiden University Medical Center, The Netherlands , (Netherlands)
  • 3 Sarcoma Patients EuroNet Association (SPAEN), Germany , (Germany)
  • 4 The Royal Marsden Hospital, United Kingdom , (United Kingdom)
  • 5 Brigham and Women's Hospital
  • 6 Dana‐Farber Cancer Institute
  • 7 Harvard Medical School
  • 8 National Cancer Institute, Italy , (Italy)
  • 9 Mount Sinai Hospital, Canada , (Canada)
  • 10 The Maria Sklodowska‐Curie Institute Oncology Center, Poland , (Poland)
Type
Published Article
Journal
Cancer
Publisher
Wiley (John Wiley & Sons)
Publication Date
Apr 21, 2020
Volume
126
Issue
13
Pages
3002–3012
Identifiers
DOI: 10.1002/cncr.32911
PMID: 32315454
PMCID: PMC7318349
Source
PubMed Central
Keywords
License
Unknown
External links

Abstract

This retrospective study of perioperative radiotherapy in patients with primary extrameningeal solitary fibrous tumors suggests that combining radiotherapy with surgery in the management of this population significantly reduces the risk of local failures, especially in patients who have less favorable resection margins or tumors with a high mitotic count.

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