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Extradural thoracic spinal cord compression: unusual initial presentation of post-transplant lymphoproliferative disorder.

Authors
  • Bakker, Nicholas A1
  • van Dijk, J Marc C
  • Slart, Riemer H J A
  • Coppes, Maarten H
  • van Imhoff, Gustaaf W
  • Verschuuren, Eric A M
  • 1 Department of Neurosurgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. [email protected] , (Netherlands)
Type
Published Article
Journal
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Publication Date
Oct 01, 2008
Volume
27
Issue
10
Pages
1165–1168
Identifiers
DOI: 10.1016/j.healun.2008.06.008
PMID: 18926411
Source
Medline
Language
English
License
Unknown

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after solid-organ transplantation. We report a lung transplant recipient presenting with lower limb weakness as a result of extradural cord compression from PTLD. Diagnosis was made by laminectomy of T-3 with partial removal of the epidural mass. Further treatment consisted of chemoradiotherapy. The patient recovered completely. To our knowledge, this is the first reported case of PTLD presenting with signs and symptoms of spinal cord compression. The differential diagnosis of spinal cord compression in a patient who has had a transplant should include primary presentation of PTLD.

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