Injured podocytes in active LN express TLR9. This expression could be associated with proteinuria and increased anti-dsDNA antibody. This is the first report indicating that TLR9 is involved in the aetiology of LN and that it may play some role in podocyte injury.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/20181802