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Expression of Sphingosine Kinase-1 Is Associated with Invasiveness and Poor Prognosis of Oral Squamous Cell Carcinoma.

Authors
  • Kato, Koichiro1
  • Shimasaki, Miyako2
  • Kato, Takao3
  • Segami, Natsuki3
  • Ueda, Yoshimichi2
  • 1 Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa, Japan [email protected] , (Japan)
  • 2 Department of Pathophysiological and Experimental Pathology, Kanazawa Medical University, Ishikawa, Japan. , (Japan)
  • 3 Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa, Japan. , (Japan)
Type
Published Article
Journal
Anticancer Research
Publisher
International Institute of Anticancer Research
Publication Date
Mar 01, 2018
Volume
38
Issue
3
Pages
1361–1368
Identifiers
PMID: 29491060
Source
Medline
Keywords
License
Unknown

Abstract

These results demonstrate the involvement of SphK1 in the invasiveness of OSCC and in unfavorable prognosis, indicating its role in the epithelial-mesenchymal transition of OSCC cells.

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