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Expression and significance of ICAM-1 and its counter receptors LFA-1 and Mac-1 in experimental acute pancreatitis of rats.

Authors
Type
Published Article
Journal
World Journal of Gastroenterology
1007-9327
Publisher
Baishideng Publishing Group Co
Publication Date
Volume
12
Issue
31
Pages
5005–5009
Identifiers
PMID: 16937496
Source
Medline
License
Unknown

Abstract

Our findings suggest the important role for ICAM-1, LFA-1 and Mac-1 in mediating the development of AP from a local disease to a systemic illness. Upregulation of ICAM-1, LFA-1, Mac-1 and subsequent leukocyte infiltration appear to be significant events of pancreatic and pulmonary injuries in AP.

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