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Expression of platelet-bound stromal cell-derived factor-1 in patients with non-valvular atrial fibrillation and ischemic heart disease.

Authors
  • Stellos, Konstantinos
  • Rahmann, A
  • Kilias, A
  • Ruf, M
  • Sopova, K
  • Stamatelopoulos, K
  • Jorbenadze, R
  • Weretka, S
  • Geisler, T
  • Gawaz, M
  • Weig, H-J
  • Bigalke, B
Type
Published Article
Journal
Journal of thrombosis and haemostasis : JTH
Publication Date
Jan 01, 2012
Volume
10
Issue
1
Pages
49–55
Identifiers
DOI: 10.1111/j.1538-7836.2011.04547.x
PMID: 22044645
Source
Medline
License
Unknown

Abstract

Differential expression of platelet-bound and plasma SDF-1 was observed in patients with AF compared with SR which may be involved in progenitor cell mobilization and inflammatory cell recruitment in patients with AF and ischemic heart disease. Further in vivo studies are required to elucidate the role of SDF-1 in atrial remodeling and the atrial fibrillation course.

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