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Expression of the multidrug transporter, P-glycoprotein, in renal and transitional cell carcinomas.

Authors
  • Nishiyama, K
  • Shirahama, T
  • Yoshimura, A
  • Sumizawa, T
  • Furukawa, T
  • Ichikawa-Haraguchi, M
  • Akiyama, S
  • Ohi, Y
Type
Published Article
Journal
Cancer
Publication Date
Jun 01, 1993
Volume
71
Issue
11
Pages
3611–3619
Identifiers
PMID: 8098269
Source
Medline
License
Unknown

Abstract

These data show that P-glycoprotein was expressed in many RCC, and its expression level, glycosylation, and distribution were altered. These data also suggest that the P-glycoprotein in RCC had similar drug binding site(s) to that in multidrug-resistant cells.

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