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Expression, localization and activity of neutral endopeptidase in cultured cells of benign prostatic hyperplasia and prostate cancer.

Authors
  • Albrecht, Martin
  • Gillen, Sonja
  • Wilhelm, Beate
  • Doroszewicz, Jolanta
  • Aumüller, Gerhard
Type
Published Article
Journal
The Journal of Urology
Publisher
Elsevier
Publication Date
Jul 01, 2002
Volume
168
Issue
1
Pages
336–342
Identifiers
PMID: 12050566
Source
Medline
License
Unknown

Abstract

These data suggest that neutral endopeptidase is expressed by prostatic stromal cells. In addition to its role in the progression of prostate cancer, it may also be involved in regulatory processes in the stroma, namely the degradation of neuropeptides released from prostatic neuroendocrine cells.

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