[The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].
- Published Article
Zhonghua wai ke za zhi [Chinese journal of surgery]
- Publication Date
Mar 15, 2005
Our study suggests that VHL gene mutations are frequent in sporadic CCRCC, and the high expression of HIF-1alpha and 2alpha are found in the group of VHL mutations. However, we have not found significant correlation between the expression of HIF-1alpha and 2alpha and pathological grade and stage of CCRCC in our study.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15854350