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The expression of androgen-responsive genes is up-regulated in the epithelia of benign prostatic hyperplasia.

Authors
  • O'Malley, Katherine J
  • Dhir, Rajiv
  • Nelson, Joel B
  • Bost, James
  • Lin, Yan
  • Wang, Zhou
Type
Published Article
Journal
The Prostate
Publisher
Wiley (John Wiley & Sons)
Publication Date
Dec 01, 2009
Volume
69
Issue
16
Pages
1716–1723
Identifiers
DOI: 10.1002/pros.21034
PMID: 19676094
Source
Medline
License
Unknown

Abstract

Androgen signaling is significantly elevated in BPH relative to the adjacent normal prostate. Understanding the mechanisms causing elevated androgen signaling may lead to novel approaches for prevention and/or treatment of BPH.

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