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Exploring the synthetic biology potential of bacteriophages for engineering non-model bacteria

Authors
  • Lammens, Eveline-Marie1
  • Nikel, Pablo Ivan2
  • Lavigne, Rob1
  • 1 KU Leuven, Kasteelpark Arenberg 21 box 2462, Leuven, BE, 3001, Belgium , Leuven (Belgium)
  • 2 Technical University of Denmark, Kemitorvet, Building 220, Lyngby, DK, 2800 Kgs, Denmark , Lyngby (Denmark)
Type
Published Article
Journal
Nature Communications
Publisher
Springer Nature
Publication Date
Oct 20, 2020
Volume
11
Issue
1
Identifiers
DOI: 10.1038/s41467-020-19124-x
Source
Springer Nature
License
Green

Abstract

Non-model bacteria offer unique and versatile metabolisms for synthetic biology. In this Perspective, the authors explore the limited availability of well-characterised biological parts in these species and argue that bacteriophages represent a diverse trove of orthogonal parts.

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