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Exploring the idiotypes of insulin antibodies as markers for remission in Type 1 diabetes.

Authors
  • Devendra, D
  • Galloway, T S
  • Horton, S J
  • Wilkin, T J
Type
Published Article
Journal
Diabetic medicine : a journal of the British Diabetic Association
Publication Date
Dec 01, 2004
Volume
21
Issue
12
Pages
1316–1324
Identifiers
PMID: 15569135
Source
Medline
License
Unknown

Abstract

We have established the principle of using phage display in the investigation of insulin antibodies during remission in Type 1 diabetes. The immunological characteristics of IA 3 months after the introduction of insulin treatment were different from those at diagnosis of Type 1 diabetes (IAA). Using phage display technology, it was not possible to distinguish insulin antibodies according to remission status.

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