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Experiences from tissue microarray in soft tissue sarcomas.

Authors
  • Nilbert, M
  • Engellau, J
Type
Published Article
Journal
Acta orthopaedica Scandinavica. Supplementum
Publication Date
Apr 01, 2004
Volume
75
Issue
311
Pages
29–34
Identifiers
PMID: 15188663
Source
Medline
License
Unknown

Abstract

The tissue microarray (TMA) technology was introduced in 1998 as a tissue preserving, high-throughput technique that allows studies of multiple markers in large sample sets. TMA slides can be analyzed using techniques such as immunohistochemistry and in situ hybridization and represents a powerful tool for the investigation of potential diagnostic and prognostic markers identified in DNA microarray studies. We review the TMA method, its reproducibility, advantages, limitations and future perspectives with specific focus on soft tissue sarcomas.

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