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Expanding options in radiation oncology: neutron beam therapy.

Authors
Type
Published Article
Journal
Journal of the Royal Society of Medicine
Publication Date
Volume
75
Issue
6
Pages
394–398
Identifiers
PMID: 6806472
Source
Medline
License
Unknown

Abstract

Twelve years' experience with neutron beam therapy in Britain, the USA, Europe and Japan shows that local control is achievable in late-stage epidermoid cancer somewhat more frequently than with conventional radiotherapy. Tumours reputed to be radioresistant (salivary gland, bladder, rectosigmoid, melanoma, bone and soft-tissue sarcomas) have proved to be particularly responsive to neutrons. Pilot studies in brain and pancreatic tumours suggest promising new approaches to management of cancer in these sites. The availability of neutron therapy in the clinical environment opens new prospects for irradiation of 'radioresistant' tumours, permits more conservative cancer surgery, expands the use of elective chemotherapy and provides a wider range of options for cancer patients.

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