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Exosomal-like vesicles with immune-modulatory features are present in human plasma and can induce CD4+ T-cell apoptosis in vitro.

Authors
  • Ren, Yana
  • Yang, Jie
  • Xie, Rufeng
  • Gao, Li
  • Yang, Yiming
  • Fan, Huahua
  • Qian, Kaicheng
Type
Published Article
Journal
Transfusion
Publication Date
May 01, 2011
Volume
51
Issue
5
Pages
1002–1011
Identifiers
DOI: 10.1111/j.1537-2995.2010.02909.x
PMID: 21044087
Source
Medline
License
Unknown

Abstract

Exosomes present in human plasma contain immunity-associated molecules and can induce CD4+ T-cell apoptosis in vitro. Plasma exosomes have the capacity to influence immune responses.

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