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[Exosomal biomarkers for kidney disease.]

Authors
  • Hosojima, Michihiro1
  • Kabasawa, Hideyuki1
  • Kuwahara, Shoji2
  • Saito, Akihiko2
  • 1 Department of Clinical Nutrition Science, Kidney Research Center, Niigata University, Japan. , (Japan)
  • 2 Department of Applied Molecular Medicine, Kidney Research Center, Niigata University, Japan. , (Japan)
Type
Published Article
Journal
Clinical calcium
Publication Date
Jan 01, 2018
Volume
28
Issue
2
Pages
252–259
Identifiers
DOI: CliCa1802252259
PMID: 29371492
Source
Medline
License
Unknown

Abstract

Development of minimally invasive biomarkers is necessary for early detection, prognosis prediction, severity assessment and treatment monitoring in different kidney diseases. Recently, many studies have been conducted worldwide on marker proteins and micro RNA(miRNA)contained in urinary extracellular vesicles(EVs)including exosomes. This article reviews urinary EV-contained biomarkers, including proximal tubular endocytic receptor megalin, for kidney diseases such as diabetic nephropathy.

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