Exact vs. approximate computation: reconciling different estimates of Mycobacterium tuberculosis epidemiological parameters.
School of Mathematics and Statistics, University of New South Wales, Sydney, NSW 2052 Australia.
- Published Article
The Genetics Society of America
- Publication Date
Apr 01, 2014
Exact computational methods for inference in population genetics are intuitively preferable to approximate analyses. We reconcile two starkly different estimates of the reproductive number of tuberculosis from previous studies that used the same genotyping data and underlying model. This demonstrates the value of approximate analyses in validating exact methods.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/24496011