Affordable Access

deepdyve-link
Publisher Website

Evolutionary mechanisms for establishing eukaryotic cellular complexity

Authors
  • Mast, Fred D.
  • Barlow, Lael D.
  • Rachubinski, Richard A.
  • Dacks, Joel B.1, 2, 3, 4
  • 1 Department of Cell Biology
  • 2 University of Alberta
  • 3 Seattle Biomedical Research Institute
  • 4 Institute for Systems Biology
Type
Published Article
Journal
Trends in Cell Biology
Publisher
Elsevier
Publication Date
Jan 01, 2014
Identifiers
DOI: 10.1101/CSHPERSPECT.a01604
Source
Elsevier
Keywords
License
Unknown

Abstract

Through a comparative approach, evolutionary cell biology makes use of genomics, bioinformatics, and cell biology of non-model eukaryotes to provide new avenues for understanding basic cellular processes. This approach has led to proposed mechanisms underpinning the evolution of eukaryotic cellular organization including endosymbiotic and autogenous processes and neutral and adaptive processes. Together these mechanisms have contributed to the genesis and complexity of organelles, molecular machines, and genome architecture. We review these mechanisms and suggest that a greater appreciation of the diversity in eukaryotic form has led to a more complete understanding of the evolutionary connections between organelles and the unexpected routes by which this diversity has been reached.

Report this publication

Statistics

Seen <100 times