The evolution and evaluation of a whole blood polymerase chain reaction assay for the detection of invasive aspergillosis in hematology patients in a routine clinical setting.
- Published Article
Clinical Infectious Diseases
Oxford University Press
- Publication Date
Feb 15, 2006
A negative PCR result can be used to rule out IA and to limit the need for empirical antifungal therapy; thus, it has a role in diagnosing IA infections, especially in combination with antigen testing. PCR-positive cases classified as "false positives" regularly reflect the limitations of classic microbiological procedures or restricted use of consensus clinical methods employed to classify infection.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/16421791