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Evoked potentials and EEG in multiple sclerosis.

Authors
  • Pakalnis, A
  • Drake, M E Jr
  • Dadmehr, N
  • Weiss, K
Type
Published Article
Journal
Electroencephalography and Clinical Neurophysiology
Publisher
Elsevier
Publication Date
Oct 01, 1987
Volume
67
Issue
4
Pages
333–336
Identifiers
PMID: 2441967
Source
Medline
License
Unknown

Abstract

Thirteen patients with clinically definite multiple sclerosis (MS) were studied with electroencephalogram (EEG), magnetic resonance imaging (MRI), evoked potentials and cerebrospinal fluid (CSF) analysis. We attempted to correlate the findings with physical disability as defined by Kurtzke score and presence of dementia or seizures. More severe plaque disease on MRI and increased physical disability correlated significantly with abnormality on brain-stem auditory evoked potentials (BAEPs) while visual evoked potential (VEP) abnormality correlated only with MRI findings. No such correlation was found with the EEG. The close relationship between BAEP and MRI abnormalities probably reflects frequent involvement of brain-stem corticospinal pathways.

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